Publications dans lesquelles il/elle collabore avec Joaquín María Campos Rosa (23)

2015

  1. P-Nitrobenzenesulfonamides and their fluorescent dansylsulfonamides derived from N-alkylated o-(purine-methyl)anilines as novel antitumour agents

    RSC Advances, Vol. 5, Núm. 93, pp. 76615-76619

2014

  1. Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)- 9H- or 7H-purines against several human solid tumour cell lines

    European Journal of Medicinal Chemistry, Vol. 76, pp. 118-124

  2. HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound

    Oncotarget, Vol. 5, Núm. 11, pp. 3590-3606

2013

  1. Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

    Drug Design, Development and Therapy, Vol. 7, pp. 1301-1313

2012

  1. The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis

    European Journal of Medicinal Chemistry, Vol. 50, pp. 376-382

2011

  1. Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5- tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 3802-3809

2008

  1. Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies

    Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 4, pp. 1457-1460

  2. Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines

    European Journal of Medicinal Chemistry, Vol. 43, Núm. 8, pp. 1742-1748

  3. Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin- 3-ylmethyl)-9H-purines

    ChemMedChem, Vol. 3, Núm. 1, pp. 127-135

2007

  1. 5-fluorouracil derivatives induce differentiation mediated by tubulin and HLA class I modulation

    Medicinal Chemistry, Vol. 3, Núm. 3, pp. 233-239

  2. 6′-Chloro-7- or 9-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)-7H- or 9H-purines and their corresponding sulfones as a new family of cytotoxic drugs

    Tetrahedron, Vol. 63, Núm. 1, pp. 183-190

  3. A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells

    Breast Cancer Research and Treatment, Vol. 105, Núm. 3, pp. 237-246

  4. Antiproliferative activity, cell-cycle dysregulation, and cellular differentiation: Salicyl- and catechol-derived acyclic 5-fluorouracil O,N-acetals against breast cancer cells

    ChemMedChem, Vol. 2, Núm. 12, pp. 1814-1821

2006

  1. Differentiation: An encouraging approach to anticancer therapy

    Italian Journal of Anatomy and Embryology, Vol. 111, Núm. 1, pp. 45-64

  2. Synthesis and anticancer activity studies of novel 1-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)uracil and (6′-substituted)-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or 9H-purines

    Tetrahedron, Vol. 62, Núm. 50, pp. 11724-11733

2005

  1. Antitumoural properties of benzannelated seven-membered 5-fluorouracil derivatives and related open analogues. Molecular markers for apoptosis and cell cycle dysregulation

    Farmaco

  2. New medium oxacyclic O,N-acetals and related open analogues: Biological activities

    Current Medicinal Chemistry, Vol. 12, Núm. 12, pp. 1423-1438

  3. Synthesis of novel 1-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)-uracil and -thymine, and their corresponding S-oxidized derivatives

    Tetrahedron, Vol. 61, Núm. 43, pp. 10363-10369

2004

  1. Actual targets in cytodifferentiation cancer therapy

    Current Topics in Medicinal Chemistry, Vol. 4, Núm. 2, pp. 175-202

  2. Growth inhibition, G 1-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives

    Investigational New Drugs, Vol. 22, Núm. 4, pp. 379-389