CIENCIAS DE LA SALUD
Departamento
Miguel Ángel
Gallo Mezo
Publicaciones en las que colabora con Miguel Ángel Gallo Mezo (19)
2012
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The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis
European Journal of Medicinal Chemistry, Vol. 50, pp. 376-382
2011
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Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5- tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine
European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 3802-3809
2008
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Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies
Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 4, pp. 1457-1460
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Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines
European Journal of Medicinal Chemistry, Vol. 43, Núm. 8, pp. 1742-1748
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Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin- 3-ylmethyl)-9H-purines
ChemMedChem, Vol. 3, Núm. 1, pp. 127-135
2007
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5-fluorouracil derivatives induce differentiation mediated by tubulin and HLA class I modulation
Medicinal Chemistry, Vol. 3, Núm. 3, pp. 233-239
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6′-Chloro-7- or 9-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)-7H- or 9H-purines and their corresponding sulfones as a new family of cytotoxic drugs
Tetrahedron, Vol. 63, Núm. 1, pp. 183-190
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A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells
Breast Cancer Research and Treatment, Vol. 105, Núm. 3, pp. 237-246
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Antiproliferative activity, cell-cycle dysregulation, and cellular differentiation: Salicyl- and catechol-derived acyclic 5-fluorouracil O,N-acetals against breast cancer cells
ChemMedChem, Vol. 2, Núm. 12, pp. 1814-1821
2006
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Synthesis and anticancer activity studies of novel 1-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)uracil and (6′-substituted)-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or 9H-purines
Tetrahedron, Vol. 62, Núm. 50, pp. 11724-11733
2005
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Antitumoural properties of benzannelated seven-membered 5-fluorouracil derivatives and related open analogues. Molecular markers for apoptosis and cell cycle dysregulation
Farmaco
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New medium oxacyclic O,N-acetals and related open analogues: Biological activities
Current Medicinal Chemistry, Vol. 12, Núm. 12, pp. 1423-1438
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Synthesis of novel 1-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)-uracil and -thymine, and their corresponding S-oxidized derivatives
Tetrahedron, Vol. 61, Núm. 43, pp. 10363-10369
2004
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Actual targets in cytodifferentiation cancer therapy
Current Topics in Medicinal Chemistry, Vol. 4, Núm. 2, pp. 175-202
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Growth inhibition, G 1-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives
Investigational New Drugs, Vol. 22, Núm. 4, pp. 379-389
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Synthesis of tetrahydrobenzoxazepine acetals with electron-withdrawing groups on the nitrogen atom. Novel scaffolds endowed with anticancer activity against breast cancer cells
Tetrahedron, Vol. 60, Núm. 50, pp. 11547-11557
2003
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Medium benzene-fused oxacycles with the 5-fluorouracil moiety: Synthesis, antiproliferative activities and apoptosis induction in breast cancer cells
Tetrahedron, Vol. 59, Núm. 29, pp. 5457-5467
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Neighbouring-group participation as the key step in the reactivity of acyclic and cyclic salicyl-derived O,O-acetals with 5-fluorouracil. Antiproliferative activity, cell cycle dysregulation and apoptotic induction of new O,N-acetals against breast cancer cells
Tetrahedron, Vol. 59, Núm. 40, pp. 8017-8026
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Synthesis and evaluation of new 5-fluorouracil antitumor cell differentiating derivatives
Bioorganic and Medicinal Chemistry, Vol. 11, Núm. 3, pp. 315-323