Publicacions (403) Publicacions de JUSTO COBO DOMINGO

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2025

  1. Synthesis and structural analysis of 1,4′-pyrazolo[3,4-e][1,4]thiazepin-7′(6H)ones: An example of conformational chirality in seven-membered heterocycles

    Journal of Molecular Structure, Vol. 1322

2024

  1. Alternative and efficient one-pot three-component synthesis of substituted 2-aryl-4-styrylquinazolines/4-styrylquinazolines from synthetically available 1-(2-aminophenyl)-3-arylprop-2-en-1-ones: characterization and evaluation of their antiproliferative activities

    RSC Advances, Vol. 14, Núm. 29, pp. 20951-20965

  2. Cascade Synthesis of New Indole-Containing Pentacyclic Scaffolds Mediated by Aryl and Iminyl Radicals

    Chemistry - An Asian Journal, Vol. 19, Núm. 5

  3. Regioselective Synthesis of Cycloalkane-fused Pyrazolo[4,3-e]pyridines through Tandem Reaction of 5-aminopyrazoles, Cyclic Ketones and Electron-rich Olefins

    Current Organic Synthesis, Vol. 21, Núm. 7, pp. 947-956

  4. Rosmarinic Acid Present in Lepechinia floribunda and Lepechinia meyenii as a Potent Inhibitor of the Adenylyl Cyclase gNC1 from Giardia lamblia

    Plants, Vol. 13, Núm. 5

  5. Second generation of pyrimidin-quinolone hybrids obtained from virtual screening acting as sphingosine kinase 1 inhibitors and potential anticancer agents

    Bioorganic Chemistry, Vol. 144

  6. Synthesis and hLDHA Inhibitory Activity of New Stiripentol-Related Compounds of Potential Use in Primary Hyperoxaluria

    International Journal of Molecular Sciences, Vol. 25, Núm. 24

  7. Synthesis of Ethyl Pyrimidine-Quinolincarboxylates Selected from Virtual Screening as Enhanced Lactate Dehydrogenase (LDH) Inhibitors

    International Journal of Molecular Sciences, Vol. 25, Núm. 17

2023

  1. Synthesis of 5-(arylmethylideneamino)-4-(1H-benzo[d]imidazol-1-yl)pyrimidine hybrids: synthetic sequence and the molecular and supramolecular structures of two intermediates and three final products

    Acta crystallographica. Section C, Structural chemistry, Vol. 79, pp. 227-236

2022

  1. Design and Synthesis of New Pyrimidine-Quinolone Hybrids as Novel hLDHA Inhibitors

    Pharmaceuticals, Vol. 15, Núm. 7

  2. Influence of the Lewis basicity hardness of crystallization solvents on the coordination sphere of the complex [Co(3,5-dinitrobenzoate-O,O′)2]: crystallographic and theoretical analysis

    CrystEngComm, Vol. 24, Núm. 16, pp. 2982-2991

  3. Reactivity of pyrimidinylphosphazenes with acetylenic esters: Competitive [4 + 2] and [2 + 2] tandem cycloaddition or retro-cycloaddition approaches

    Journal of Heterocyclic Chemistry, Vol. 59, Núm. 9, pp. 1519-1532

  4. Synthesis and spectroscopic and structural characterization of three new 2-methyl-4-styrylquinolines formed using Friedländer reactions between (2-aminophenyl)chalcones and acetone

    Acta crystallographica. Section C, Structural chemistry, Vol. 78, pp. 524-530

  5. Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety

    International journal of molecular sciences, Vol. 23, Núm. 20

  6. Synthesis, and spectroscopic and structural characterization of three new styrylquinoline-benzimidazole hybrids

    Acta crystallographica. Section C, Structural chemistry, Vol. 78, pp. 671-680

2021

  1. Aambient-temperature synthesis of (E)-n-(3-(tert-butyl)-1-m methyl-1h-pyrazol-5-yl)-1-(pyridin-2-yl)methanimine thyl-1h-pyrazol-5-yl)-1-(pyridin-2-yl)methanimine

    MolBank, Vol. 2021, Núm. 3

  2. Design, synthesis, and molecular docking study of novel quinoline-based bis-chalcones as potential antitumor agents

    Archiv der Pharmazie, Vol. 354, Núm. 9

  3. Easy Access to Novel Tetrahydro-1-benzazepine-2-carboxylic Acids and Tetrahydro-1-benzazepines Carrying [a]-Fused Heterocyclic Units from 2-(Allylaryl)glycinates

    Synthesis (Germany), Vol. 53, Núm. 7, pp. 1315-1330

  4. Structure activity relationships and the binding mode of quinolinone-pyrimidine hybrids as reversal agents of multidrug resistance mediated by P-gp

    Scientific Reports, Vol. 11, Núm. 1

  5. Synthesis and spectroscopic and structural characterization of spiro[indoline-3,3′-indolizine]s formed by 1,3-dipolar cycloadditions between isatins, pipecolic acid and an electron-deficient alkene

    Acta Crystallographica Section C: Structural Chemistry, Vol. 77, pp. 496-504