GRUPO INVESTIGACION EN COMPUESTOS INTERES BIOLOGICO (GICIB)
Universidad Industrial de Santander
Bucaramanga, ColombiaPublicaciones en colaboración con investigadores/as de Universidad Industrial de Santander (45)
2024
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Alternative and efficient one-pot three-component synthesis of substituted 2-aryl-4-styrylquinazolines/4-styrylquinazolines from synthetically available 1-(2-aminophenyl)-3-arylprop-2-en-1-ones: characterization and evaluation of their antiproliferative activities
RSC Advances, Vol. 14, Núm. 29, pp. 20951-20965
2022
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Synthesis and spectroscopic and structural characterization of three new 2-methyl-4-styrylquinolines formed using Friedländer reactions between (2-aminophenyl)chalcones and acetone
Acta crystallographica. Section C, Structural chemistry, Vol. 78, pp. 524-530
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Synthesis, and spectroscopic and structural characterization of three new styrylquinoline-benzimidazole hybrids
Acta crystallographica. Section C, Structural chemistry, Vol. 78, pp. 671-680
2021
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Easy Access to Novel Tetrahydro-1-benzazepine-2-carboxylic Acids and Tetrahydro-1-benzazepines Carrying [a]-Fused Heterocyclic Units from 2-(Allylaryl)glycinates
Synthesis (Germany), Vol. 53, Núm. 7, pp. 1315-1330
2020
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4-Styrylquinolines from cyclocondensation reactions between (2-aminophenyl)chalcones and 1,3-diketones: Crystal structures and regiochemistry
Acta Crystallographica Section C: Structural Chemistry, Vol. 76, pp. 883-890
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Straightforward Synthesis of Novel 4-Styrylquinolines/4-Styrylquinolin-2-ones and 9-Styryldihydroacridin-1(2 H)-ones from Substituted 2′-Aminochalcones
Synthesis (Germany), Vol. 52, Núm. 12, pp. 1804-1822
2019
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A concise and efficient concurrent synthesis of 6,11-dihydrodibenzo[b,e]azepines and 5,6,11,12-tetrahydrodibenzo[b,f]azocines and their conversion to 4-oxo-8,13-dihydro-4H-benzo[5,6]aze-pino[3,2,1-ij]quinoline-5-carboxylates and N-acetyl-5,6,11,12-tetrahydrodibenzo[b,f]azocines: Synthetic sequence, spectroscopic characterization and the structures of two products
Acta Crystallographica Section C: Structural Chemistry, Vol. 75, pp. 650-656
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A concise and versatile route to tetrahydro-1-benzazepines carrying [a]-fused heterocyclic units: Synthetic sequence and spectroscopic characterization, and the molecular and supramolecular structures of one intermediate and two products
Acta Crystallographica Section C: Structural Chemistry, Vol. 75, pp. 168-177
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Monoclinic and orthorhombic forms of (Rs)-(e)-4-[2-(4-chlorobenzylidene)hydrazinyl]-6,11-dimethyl-6,11-dihydro-5h-benzo[b]pyrimido[5,4-f]azepine: Synthesis, concomitant polymorphism and supramolecular assembly mediated by C—H…N, C—H…π(arene) and C—CL…π(arene) interactions
Acta Crystallographica Section C: Structural Chemistry, Vol. 75, pp. 686-693
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Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti-inflammatory activity
Archiv der Pharmazie, Vol. 352, Núm. 3
2017
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An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors
European Journal of Medicinal Chemistry, Vol. 139, pp. 461-481
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Three tetracyclic dibenzoazepine derivatives exhibiting different molecular conformations, different patterns of intermolecular hydrogen bonding and different modes of supramolecular aggregation
Acta Crystallographica Section C: Structural Chemistry, Vol. 73, Núm. 1, pp. 28-35
2016
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Diastereoisomeric forms of 11-ethyl-6,11-dihydro-5H-dibenzo[b,e]azepine-6-carboxamide: syntheses and the molecular and supramolecular structure of the minor form (6RS,11RS)-11-ethyl-6,11-dihydro-5H-dibenzo[b,e]azepine-6-carboxamide
Acta Crystallographica Section C: Structural Chemistry, Vol. 72, Núm. 7, pp. 549-554
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Similar molecular constitutions but different conformations and different supramolecular assemblies in two related fused tetracyclic benzo[b]pyrimido[5,4-f]azepine derivatives
Acta Crystallographica Section C: Structural Chemistry, Vol. 72, pp. 52-56
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Six polycyclic pyrimidoazepine derivatives: Syntheses, molecular structures and supramolecular assembly
Acta Crystallographica Section C: Structural Chemistry, Vol. 72, Núm. 4, pp. 346-357
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Unexpected ring-closure products derived from 3-(2-allylanilino)-3-phenylacrylate esters: Crystal and molecular structures of 3-acetyl-8-allyl-6-methyl-2-phenylquinolin-4-yl acetate and (2RS)-2,8-dimethyl-4-phenyl-1,2-dihydro-6H-pyrrolo[3,2,1-ij]quinolin-6-one
Acta Crystallographica Section C: Structural Chemistry, Vol. 72, Núm. 8, pp. 619-626
2015
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Five closely related 4-chloro-6,11-dihydro-5H-benzo[b]pyrimido[5,4-f]azepines: Similar molecular structures but different supramolecular assemblies
Acta Crystallographica Section C: Structural Chemistry, Vol. 71, pp. 1062-1068
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Synthesis of Pyrimidine-Fused Benzazepines from 5-Allyl-4,6-dichloropyrimidines
European Journal of Organic Chemistry, Vol. 2015, Núm. 24, pp. 5360-5369
2014
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1-(2-Allylaryl)-1 H -Pyrroles as Building Blocks for Novel 4-Methyl-4,5-diÂhydropyrrolo[1,2- A ]quinoline Derivatives
Synlett, Vol. 25, Núm. 2, pp. 243-246
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Four related benzazepine derivatives in a reaction pathway leading to a benzazepine carboxylic acid: Hydrogen-bonded assembly in zero, one, two and three dimensions
Acta Crystallographica Section C: Structural Chemistry, Vol. 70, Núm. 4, pp. 408-415