Análisis de la diversidad de resistomas y virulomas en un matadero a lo largo de la cadena de producción de la carne

  1. CAMPOS CALERO, GUILLERMO
Dirigida por:
  1. Hikmate Abriouel Ayani Directora
  2. Natacha Caballero Gómez Codirectora
  3. Nabir Ben Omar el Bakali Codirector/a

Universidad de defensa: Universidad de Jaén

Fecha de defensa: 12 de julio de 2021

Tribunal:
  1. Mohamed Larbi Merroun Presidente/a
  2. Leire Lavilla Lerma Secretaria
  3. María Luisa Grande Gascón Vocal
Departamento:
  1. CIENCIAS DE LA SALUD

Tipo: Tesis

Teseo: 680233 DIALNET lock_openRUJA editor

Resumen

In this study, resistome and virulome patterns were determined, in order to monitor the possible contamination along the meat production chain. By means of culture-dependent and independent methods (metagenomics), high levels of microbial contamination were detected on surfaces of both animals and processing areas. In addition, a great diversity and abundance of antibiotic resistance genes (ARGs) and virulence determinants (VRGs) were obtained, which represents a potential risk for public health. Subsequently, the microbial ecology and the functional genes abundantly associated with stress genes were determined, especially in the first production areas (most contaminated areas). And to prevent the spread of microbial contaminants and their resistance / virulence genes, the HLE disinfectant was used, which performed best when combined with a pre-cleaning with detergent.