Evaluación de la corresistencia a metales pesados y antibióticos en microorganismos procedentes de suelos de olivar ecológico y tradicional de la provincia de Jaén. Mecanismos moleculares implicados

  1. Glibota Rschichuchi, Nicolás Alejandro
Supervised by:
  1. Elena Ortega Morente Director
  2. Antonio Gálvez del Postigo Ruiz Co-director
  3. María José Grande Burgos Co-director

Defence university: Universidad de Jaén

Fecha de defensa: 13 December 2019

Committee:
  1. Mª Carmen Millán Pérez Chair
  2. Rosario Lucas López Secretary
  3. Samir Ananou Committee member
Department:
  1. CIENCIAS DE LA SALUD

Type: Thesis

Teseo: 615804 DIALNET

Abstract

There is growing concern about heavy metal pollution as a persistent selective pressure that favours the spread of antimicrobial resistance in natural environments. The aim of this study was to isolate and identify metal tolerant bacteria from soils in olive tree fields treated with copper compounds, to evaluate the tolerance of bacterial strains to other metals and their resistance to clinically relevant antibiotics. We have also evaluated possible significant associations between metal tolerance and antibiotic resistance. In conclusion, bacteria from olive soils are tolerant to metals, mainly copper, also Zn and Pb, and in lower percentages to Cd and Ni, as well as resistant to clinically important antibiotics, which could be a problem in clinical settings. Co-occurrence of metal tolerance and antibiotic resistance genes together with the significant associations found between both types of genes may provide additional clues for understanding possible roles of metal-tolerance genes in co-selection of antibiotic resistances.