Última generación de sistemas luminiscentes multiconmutados en flujo con aplicación en los campos agroalimentario y farmacológico

Résumé

In this Report, several scientific/technical improvements concerning the development and the application of automated flow systems are proposed. The systems developed were applied to the analysis of molecules of different nature in the pharmacological and agri-food fields, showing its versatility and its analytical applicability. The research here described gave origin to nine scientific publications in scientific international journals. Special emphasis was placed on increasing the level of automation of the flow sensors described to date, particularly improving the potential of multicommutated flow injection analysis methods. The selection of luminescent detection techniques was performed by paying special attention to two aspects: a) increasing the selectivity of the analytical methods; b) the use of detection techniques that have been underused in flow systems, such as Photochemically Induced Fluorescence. Likewise, fluorescent nanoparticles have been used to carry out the luminescent determination of analytes that do not exhibit native fluorescence.